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Wat volgt is een lijst van wetenschappelijke artikelen waaraan recent subsidie werd toegekend door de Universitaire Stichting. De artikelen zijn gesorteerd op jaar van uitgave en per titel.
Nephroprotective Effects of Two Ganoderma Species Methanolic Extracts in an In Vitro Model of Cisplatin Induced Tubulotoxicity
Antoine, M.-H.;Welti, S.; Stévigny, C.; Nortier, J. Nephroprotective Effects of Two Ganoderma Species Methanolic Extracts in an In Vitro Model of Cisplatin Induced Tubulotoxicity. J. Fungi 2022, 8, 1002. https://doi.org/10.3390/jof8101002
Although cisplatin is used as a first-line therapy in many cancers, its nephrotoxicity remains a real problem. Acute kidney injuries induced by cisplatin can cause proximal tubular necrosis, possibly leading to interstitial fibrosis, chronic dysfunction, and finally to a cessation of chemotherapy. There are only a few nephroprotective actions that can help reduce cisplatin nephrotoxicity. This study aims to identify new prophylactic properties with respect to medicinal mushrooms.
Tori F. & Ginis V. Phase space approach to solving higher order differential equations with artificial neural networks. Physical Review Research vol. 4, 043090.
The ability to solve differential equations represents a key step in the modeling and understanding of complex systems. There exist several analytical and numerical methods for solving differential equations, each with their own advantages and limitations. Physics-informed neural networks (PINNs) offer an alternative perspective. Although PINNs deliver promising results, many stones remain unturned about this method. In this paper, we introduce a method that improves the efficiency of PINNs in solving differential equations.
Physicians’ Experiences and Perceptions of Environmental Factors Affecting Their Practices of Continuous Deep Sedation until Death: A Secondary Qualitative Analysis of an Interview Study
As previous research has paid little attention to environmental factors affecting the practice of continuous deep sedation until death (CDS), we aimed to explore these using physicians’ experiences and perceptions.
Opsomer S, Lauwerier E, De Lepeleire J, Pype P. Resilience in advanced cancer caregiving. A systematic review and meta-synthesis. Palliative Medicine. 2022;36(1):44-58. doi:10.1177/02692163211057749
Role of the cellular factor CTCF in the regulation of bovine leukemia virus latency and three-dimensional chromatin organization
Bellefroid M, Rodari A, et al. (2022) Role of the cellular factor CTCF in the regulation of bovine leukemia virus latency and three-dimensional chromatin organization. Nucleic Acids Res. Apr 8;50(6):3190-3202. doi: 10.1093/nar/gkac107. PMID: 35234910; PMCID: PMC8989512.
Bovine leukemia virus (BLV)-induced tumoral development is a multifactorial phenomenon that remains incompletely understood. Here, we highlight the critical role of the cellular CCCTC-binding factor (CTCF) both in the regulation of BLV transcriptional activities and in the deregulation of the three-dimensional (3D) chromatin architecture surrounding the BLV integration site. We demonstrated the in vivo recruitment of CTCF to three conserved CTCF binding motifs along the provirus.
Safety Culture and the Positive Association of Being a Primary Care Training Practice during COVID-19: The Results of the Multi-Country European PRICOV-19 Study
Simple and Scalable Chemical Surface Patterning via Direct Deposition from Immobilized Plasma Filaments in a Dielectric Barrier Discharge
Demaude, A., Petitjean, D., Zveny, J., Reniers, F. et al. (2022) Simple and Scalable Chemical Surface Patterning via Direct Deposition from Immobilized Plasma Filaments in a Dielectric Barrier Discharge. Adv. Sci., 2200237. DOI: 10.1002/advs.202200237
In this work, immobilization of the often unwanted filaments in dielectric barrier discharges (DBD) is achieved and used for one-step deposition of patterned coatings. By texturing one of the dielectric surfaces, a discharge containing stationary plasma filaments is ignited in a mix of argon and propargyl methacrylate (PMA) in a reactor operating at atmospheric pressure. From PMA, hydrophobic and hydrophilic chemical and topographical contrasts at sub-millimeter scale are obtained on silicon and glass substrates.
Standard language dynamics in postcolonial Suriname Measuring language attitudes and ideologies in Paramaribo
Ghyselen, A.-S., Grondelaers, S et al. (2022) Standard language dynamics in postcolonial Suriname Measuring language attitudes and ideologies in Paramaribo. Lingua, Vol. 273, 103340. https://doi.org/10.1016/j.lingua.2022.103340
This paper reports a large-scale survey into the language attitudes of 485 participants from the Surinamese capital Paramaribo. Suriname is an interesting arena for standard language research, as the country is steeped in multilingualism but regards the Dutch of its former colonizer as its only official language. We elicited evaluations of 10 languages spoken in Suriname in response to label- and audio-based stimuli. Responses were enriched with valence information (pertaining to their positive/negative character), and subjected to qualitative scrutiny and regression analysis.
Study protocol for an adapted personal project analysis to measure vertical inter‑goal relations on physical activity and diet
Kassas S. et al. (2022) Study protocol for an adapted personal project analysis to measure vertical inter‑goal relations on physical activity and diet. BMC Psychology. 10:225 https://doi.org/10.1186/s40359-022-00931-4
Background: The promotion of multiple healthy lifestyles has been implemented as part of public health efforts to prevent and reduce the burden of non-communicable diseases. However, these interventions have shown a heterogeneity in their effectiveness. The pursuit of multiple daily goals may influence overall progress in achieving health goals. Horizontal inter-goal relations can be conflicting (due to time constraints) or facilitating (due to goal compatibility) and impact progress towards goal achievement.
The Halophyte Species Solanum chilense Dun. Maintains Its Reproduction despite Sodium Accumulation in Its Floral Organs
Salinity is a growing global concern that affects the yield of crop species, including tomato (Solanum lycopersicum). Its wild relative Solanum chilense was reported to have halophyte properties. We compared salt resistance of both species during the reproductive phase, with a special focus on sodium localization in the flowers. Plants were exposed to NaCl from the seedling stage. Salinity decreased the number of inflorescences in both species but the number of flowers per inflorescence and sepal length only in S. lycopersicum. External salt supply decreased the stamen length in S.
Vanhoyweghen, A., Verbeken, B., Macharis, C. et al. The influence of ergodicity on risk affinity of timed and non-timed respondents. Sci Rep 12, 3744 (2022). https://doi.org/10.1038/s41598-022-07613-6
Expected values are the metric most often used to judge human decision-making; when humans make decisions that do not optimize expected values, these decisions are considered irrational. However, while convenient, expected values do not necessarily describe the evolution of an individual after making a series of decisions. This dichotomy lies at the core of ergodicity breaking, where the expected value (ensemble average) differs from the temporal average of one individual.
Sprinkle J.L. (2022) The Late Mamlūk Transition of the 1380s: The View from the North Caucasus. Al-Masāq Journal of the Medieval Mediterranean. https://doi.org/10.1080/09503110.2022.2135850.
This article argues that the transition between the early and late Mamlūk Sultanate in Egypt in the 1380s was partially caused by political developments in the Northwest Caucasus. The transition from “Turkish” to “Circassian” mamlūk dominance was facilitated by the rise of new princely elites in the Northwest Caucasus during the bulqaq civil wars in the Ulūs of Jochi (Golden Horde) (1359–1381). These new elites justified their rule through their access to the wider Mediterranean world and its material products.
Directly influenced by Colin Rowe’s essay “Mathematics of the Ideal Villa” (1947) and the Warburgian art historical tradition, John Hejduk’s nine-square grid studio exercise had an ambiguous relation to the instrumentality of architectural history. When the nine-square grid exercise was copied in many architecture schools around the world as a first-year studio project, initiating the novice student in the realm of architectural composition, the pedagogical interpretation of its relation to architectural history varied.
Lepeut A. and Shaw E. (2022) Time Is Ripe to Make Interactional Moves: Bringing Evidence From Four Languages Across Modalities. Front. Commun. 7:780124. doi: 10.3389/fcomm.2022.780124
Sign language linguistics has largely focused on lexical, phonological, and morphosyntactic structures of sign languages, leaving the facets of interaction overlooked. One reason underlying the study of smaller units in the initial stages of development of the field was a pressing concern to ground sign languages as linguistic. The interactive domain has been sidestepped in gesture studies, too, where one dominant approach has been rooted in psycholinguistic models arguing for gesture’s tight relationship with speech as part of language.
Understanding interdisciplinary perspectives of plant intelligence: Is it a matter of science, language, or subjectivity?
Khattar J., Calvo P., Vandebroek I., Pandolfi C. and Dahdouh‑Guebas F., Understanding interdisciplinary perspectives of plant intelligence: Is it a matter of science, language, or subjectivity?, Journal of Ethnobiology and Ethnomedicine, 2022, https://doi.org/10.1186/s13002-022-00539-3
Abstract Background: Evidence suggests that plants can behave intelligently by exhibiting the ability to learn, make associations between environmental cues, engage in complex decisions about resource acquisition, memorize, and adapt in flexible ways. However, plant intelligence is a disputed concept in the scientific community. Reasons for lack of consensus can be traced back to the history of Western philosophy, interpretation of terminology, and due to plants lacking neurons and a central nervous system.